ResearchTechnology

Scientists Achieve Breakthrough in Microscale Turbulence Using Supercritical Fluids

Researchers have successfully created sustained turbulent flow in microscopic channels using supercritical fluids, a phenomenon previously thought impossible at such small scales. The breakthrough, dubbed “Turbulence-On-a-Chip,” could revolutionize microfluidic applications from chemical processing to medical diagnostics. According to reports, the discovery challenges conventional understanding of fluid dynamics in confined spaces.

Revolutionizing Microfluidics with Supercritical Turbulence

Scientists have reportedly achieved what was once considered nearly impossible: creating and sustaining turbulent flow within microscopic channels. According to research published in Scientific Reports, the breakthrough was accomplished using supercritical fluids under high-pressure conditions, opening new possibilities for microfluidic applications ranging from chemical processing to biomedical diagnostics.

GeneticsScience

Single-Cell Analysis Breakthrough Enhances Detection of Genetic Regulation in Immune Responses

Scientists have developed a novel framework that captures cellular response heterogeneity to boost discovery of genetic regulators in immune cells. The approach outperforms traditional methods in identifying context-dependent genetic effects relevant to autoimmune diseases and infections. Researchers demonstrated its utility across multiple pathogen stimulations using single-cell data from hundreds of donors.

Enhanced Detection of Genetic Regulators in Cellular Responses

Researchers have developed a new analytical framework that significantly improves the detection of genetic variants that influence gene expression in response to cellular perturbations, according to a recent study published in Nature Genetics. The approach models expression quantitative trait loci (eQTLs) using a continuous perturbation score rather than binary states, reportedly increasing statistical power to identify response eQTLs (reQTLs) that change under experimental conditions.